Colloidal silica has many important applications in the high-end pharmaceutical field:

Created on 2024.12.11

Colloidal silica has many important applications in the high-end pharmaceutical field:

Pharmaceutical preparations

Thickening and thixotropic effect: In some semi-solid preparations such as topical gels and plasters, colloidal silica can increase the viscosity of the preparation. For example, in the gel of some dermatological drugs, after adding colloidal silica, the gel has high viscosity in the static state, will not flow freely, and is easy to store and transport; When subjected to a certain shear force (such as when smeared), the viscosity will temporarily decrease, making it easy to spread evenly on the skin, and after coating, it can quickly restore the state of high viscosity to avoid the free flow of drugs.

Adsorption and dispersion: For insoluble drugs, colloidal silica can adsorb drug particles and prevent them from agglomerating. In some oral suspensions, it enables the drug particles to be evenly dispersed in the liquid medium.

Cream

Colloidal silica increases the consistency of the cream, making it easier for the cream to adhere to the skin. At the same time, it can also prevent the settlement and separation of drug ingredients, ensuring the uniform distribution of drugs. During storage, the cream does not separate the oil phase from the water phase due to gravity, ensuring the accuracy and effectiveness of the drug dose every time it is used.

Inhalants

As a flow aid, the drug powder has good fluidity, but also improves the dispersion of the drug powder, so that the drug is better dispersed, more conducive to the absorption of the drug in the lung, and improves the therapeutic effect of the drug.

药品名称：布洛芬缓释胶囊
主要成分：对乙酰氨基酚
用法用量：口服，一次1-2粒，一日2-3次
不良反应：可能出现头晕、恶心等症状

Adding colloidal silica can enhance the barrier properties of pharmaceutical packaging materials, such as plastic bottles and blister packaging, effectively blocking the transmission of small molecular substances like oxygen and water vapor. This improvement helps protect the stability of drugs, particularly those prone to oxidation or humidity sensitivity, like vitamin C tablets, thereby extending the shelf life of the medications.

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