All-Round Medicinal Excipient" SYLOID® 244 FP's Nine Applications Revealed! Grace

Created on 03.26

SYLOID® 244 FP Mesoporous Silica: The Ultimate Pharmaceutical Excipient for Enhanced Drug Quality and Performance | Grace's High-Quality Medicinal Excipients Empowering Pharmaceutical Innovation and Compliance with ICH Guidelines

Grace

Medicinal excipients are critical components of pharmaceuticals, serving roles beyond mere form-giving and stabilization—they influence drug release, absorption, and bioavailability. As global regulatory standards tighten and patient demands for quality rise, high-quality excipients become indispensable for pharmaceutical companies to ensure product performance.

Grace’s Medicinal Excipients

Empowering Pharmaceutical Quality

As an innovator in silica applications, Grace provides high-quality mesoporous silica excipients that comply with ICH guidelines on elemental impurities and meet USP-NF and Ph. Eur. monographs for colloidal hydrated silica. SYLOID^{®} mesoporous silica is also listed in the FDA’s inactive ingredients database and produced under EXCiPACT^{®}-certified GMP standards.

SYLOID^{®} 244 FP Mesoporous Silica

The "All-Rounder" in Medicinal Excipients

Among Grace’s SYLOID^{®} series, SYLOID^{®} 244 FP stands out as a versatile excipient. By precisely controlling pore volume and size, it offers superior moisture protection, solubility enhancement, and bioavailability improvement, playing a pivotal role in elevating drug quality.

Slide Left to Explore SYLOID® 244 FP’s Applications

1. Glidant:

Improves powder flowability for APIs
Reduces interparticle adhesion and capillary bridging

2. Anticaking Agent:

Prevents moisture absorption in powder formulations

3. Antistatic Agent:

Minimizes electrostatic forces during production
Reduces API loss by eliminating pre-use sieving

4. Moisture Barrier:

Protects formulation stability by blocking moisture
Enhances API shelf-life

5. Tablet Hardness Improver:

Reduces sticking during compression
Strengthens tablets at lower pressures
Minimizes capping and lamination risks

6. Coating Suspension Aid:

Stabilizes suspensions to prevent nozzle clogging
Creates microstructure surfaces to reduce tablet sticking
Replaces talc in formulations

7. Flavor Absorption/Stabilization:

Adsorbs bitter tastes while enhancing antioxidation
Delays fragrance evaporation and preserves API masking

8. Oil/SEDDS Carrier:

Converts oily APIs into free-flowing powders
Facilitates solid dosage form processing

9. Solubility/Bioavailability Enhancer:

Improves NCE bioavailability
Stabilizes amorphous APIs
Prevents recrystallization through optimized pore size

Grace’s Commitment

Grace remains dedicated to delivering innovative, high-quality excipients like SYLOID^{®} 244 FP. Through continuous R&D and strict quality control, we empower pharmaceutical partners to meet evolving market demands and patient expectations.

About Grace

Grace operates two industry-leading divisions—Catalysts and Materials Technology—driving global customer success through product innovation and technical excellence.

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