ZLXIDE™ Pharmaceutical Excipient Silica - Benchmark of Multi-functional Compliant Excipients

ZLXIDE™ Pharmaceutical Excipient Silica - Benchmark of Multi-functional Compliant Excipients

In the high-quality development of the pharmaceutical, health supplement, and cosmetic industries, the compliance, stability, and multi-functionality of excipients are of vital importance. The ZLXIDE™ series of pharmaceutical excipients, silica, strictly adheres to the "Chinese Pharmacopoeia 2020 Edition IV (First Supplement)", and with its outstanding performance, has become the core excipient choice.

• Standard Compliance: In line with "Chinese Pharmacopoeia 2020 Edition IV" and the first supplement, the ordinary type (CAS: 14464-46-1) and colloidal type (CAS: 112945-52-5) are clearly classified

• High Purity: The ordinary type after calcination has SiO₂ ≥ 99.0%, and the colloidal type 99.0%-100.5%, with heavy metals ≤ 30 ppm and arsenic salts ≤ 3 ppm

• Reliable Process: Traceability throughout the process, the ordinary type is refined by precipitation, and the colloidal type is prepared by a dedicated process, with extremely low impurities

2. Multi-functional Integration, Meeting Diverse Needs

Integrating functions such as flow assistance, anti-caking, thickening, stabilization, drug loading, and sustained-release, it solves problems such as poor fluidity, caking, and uneven drug release, optimizing production processes and quality.

2. Core Product Series: Precise Segmentation for Different Scenarios

Covering 11 models, divided into the ordinary type (conventional formulations) and colloidal type (high-end formulations):

Model Core Characteristics Key Indicators Adaptable Scenarios

P58EP High oil absorption, high fluidity Specific surface area 260-300m²/g, D50 8-50μm General formulations for medicines, foods, and cosmetics

P58BT Outstanding stability Specific surface area 230-320m²/g, D50 20μm Vitamins, health supplements

P350 High oil absorption + high specific surface area Specific surface area 260-350m²/g, D50 8-50μm Highly active, oily drug formulations

P63FP/P1FP Anti-caking + flow assistance dual effect Specific surface area 85-300m²/g, D50 4-10μm Dispersions, granules, capsule filling

P244FP/P260S Gelation preparation, excellent dispersion Specific surface area 230-300m²/g, D50 4-10μm Precision solid formulations

Common Advantages: Through rate ≥ 85% on No. 7 sieve, pH 5.5-7.5, drying loss ≤ 7.0-8.5%, strong compatibility

2. Colloidal Type: Exclusive for High-end Formulations

Core models P200/P300/P380/P972, nanometer particle size (7-16nm), specific surface area 130-380m²/g, SiO₂ ≥ 99.8%; with targeted delivery, controlled-release, solubilization functions, suitable for targeted, nano, and high-purity formulations.

3. Full-Scenario Application: Covering the Entire Pharmaceutical Industry Chain

• Solid Formulations: Flow assistance improves tablet qualification rate, anti-caking extends shelf life, retention and dosage accuracy are enhanced

• Liquid Formulations: Stabilization, thickening, and prevention of aggregation and sedimentation, avoiding stratification

• Semi-solid Formulations: Adjust viscosity, optimize application experience

• New Formulations + Health Products: Empowering targeted and controlled-release research and development, stabilizing the activity of health supplements

4. Quality Control and Assurance: Whole-process Quality Protection

Test items Ordinary type standard Colloidal type standard

Particle size/drying loss ≥ 85% / ≤ 5.0% ≥ 85% / ≤ 2.5%

pH value/cremation loss 5.0-7.5 / ≤ 8.5% 3.5-5.5 / ≤ 8.5%

Chloride/sulfate/iron salt ≤ 0.1% / ≤ 0.5% / ≤ 0.015% ≤ 0.1% / ≤ 0.5% / ≤ 0.015%

2. Scientific Storage Dosage: 0.1% - 5.0% (increased in equal amounts for mixing); Store in a dry warehouse (humidity ≤ 60%), with a shelf life of 24 months; 10/15kg sealed packaging, moisture-proof and anti-contamination.

V. Enterprise Support: Professional Empowerment for Mutual Benefit

Shandong Zhonglian Chemical provides: Free samples and compatibility tests, one-on-one technical support and customized solutions, complete quality certificates and TDS files.

ZLXIDE™ is supported by compliance, performance and service, helping the industry achieve high-quality development. We look forward to working together for mutual benefit!

| (Note: Some parts of the document may be generated by AI)