Evonik's Pharmaceutical-Grade AEROSIL 200 Pharma: Nano-Scale Carrier Innovation for Global Drug and Food Industries

Evonik's Pharmaceutical-Grade AEROSIL 200 Pharma: Nano-Scale Carrier Innovation for Global Drug and Food Industries

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April 10, 2025, Hanau, Germany – Evonik, umholi omkhulu emikhiqizweni ye-chemicals ethile, namuhla umemezele ukuthi umkhiqizo wayo we-pharmaceutical-grade AEROSIL 200 Pharma (CAS No.: 112945-52-5) uthole imvume yokulawula emazweni angama-12, kuhlanganise ne-EU, U.S., kanye ne-Japan, ubeka njengemathiriyeli ethandwayo yokuthwala imithi eqinile/eyinhlama kanye nezithasiselo zokudla emhlabeni jikelele. Le colloidal silica enobukhulu obuphezulu inikeza izixazululo eziphawulekayo zokuzinza kwemithi nokuphepha kokudla ngezakhiwo zayo ze-nano-porous kanye nokuhambisana nezincwadi eziningi ze-pharmacopeia.

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I. Product Highlights: Pharmaceutical-Grade Quality & Multifunctional Performance

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AEROSIL 200 Pharma iyinhlaka ye-amorphous anhydrous colloidal silicon dioxide eyakhelwe nge-flame hydrolysis, enezici:

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- Ultra-High Purity: SiO₂ content ≥99.0% (Ph. Eur. standard), with strict control of heavy metals (≤25ppm), arsenic (≤8ppm), and other impurities, compliant with EU E551 food additive requirements.

- Nano-Scale Network Structure: Specific surface area of 175-225 m²/g and tamped density of 50 g/L ensure efficient adsorption and uniform dispersion, enhancing drug bioavailability.

- Multi-Pharmacopeia Compliance: Certified by European Pharmacopeia (Ph. Eur.), U.S. Pharmacopeia (USP/NF), Japanese Pharmacopeia (JP), and Indian Pharmacopoeia (IP), supporting global drug registration.

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II. Iparamitha Zobuchwepheshe & Ukuqhathaniswa Kwezokusebenza

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Indicator AEROSIL 200 Pharma Traditional Pharmaceutical Carriers

Specific Surface Area (BET) 175-225 m²/g 50-100 m²/g

Loss on Drying (105℃, 2h) ≤2.5% ≤5.0%

pH Value (Aqueous System) 3.5-5.5 6.0-7.0

Microbial Limits (TAMC/TYMC) ≤1000 CFU/g ≤1000 CFU/g

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III. Izimo Zokusebenza & Inani Lemboni

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1. Umkhakha Wezokwelapha

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- Solid Dosages:

- Tablets/Capsules: Iphucula ukuhamba kwepowder (ukunciphisa i-angle yokuphumula ngo-20-30%), ivimbela ukuhlanganiswa, futhi ithuthukisa ubunzima be-tablet (ngo-15-20%) kanye nokumelana nokuphuka.

- Direct Compression: Iphucula ukunciphisa kokusebenzisa ama-lubricant futhi ifinyeza izikhathi zokukhiqiza.

- Liquid Formulations:

- Suspensions/Emulsions: Isebenza njengesithako sokuthambisa kanye nesithako se-thixotropic ukuvimbela ukuhamba kwezimali (ubuningi bokuhamba >95%).

- Injectables: Compliant with IPEC-GMP standards for aseptic manufacturing.

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2. Ukudla & I-Nutraceuticals

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- Anti-Caking Agent: Maintains flowability in powdered foods (e.g., milk powder, protein powder) without caking for 6+ months under ≤60% humidity.

- Active Ingredient Carrier: Adsorbs vitamins, probiotics, etc., extending shelf life (bioactivity retention increased by 30%).

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IV. Global Footprint & Sustainability

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Evonik iqinisekisa ukuhlinzekwa kwendawo kwe-AEROSIL 200 Pharma ngokuqhuba izikhungo zokukhiqiza eHanau, eJalimane naseShanghai, eChina, enekhono lokukhiqiza elingu-5,000 amathani emetric ngonyaka. Inqubo yokukhiqiza ilandela izinhlelo ze-GMP ne-HACCP, kanti imizamo yokusimama ifaka phakathi:

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- Energy Recycling: Utilizes waste heat for power generation, reducing fossil fuel consumption.

- Packaging Optimization: Uses recyclable multi-layer paper bags (10 kg/bag) to minimize plastic waste.

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V. Ukuxhaswa Kwamakhasimende & Izigigaba Zempumelelo

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- Technical Services: A global team of 200+ experts provides full-cycle support, including:

- Ukukhululwa kokuhola (kuhlongozwa ukuxuba okuphezulu ≥30 imizuzu).

- Ukuhlolwa kokuhambisana (idatha ye-adsorption isotherm enama-API).

- Abalimi Abakhulu:

- Multinational Pharmaceutical Companies: Implemented in sustained-release tablets, achieving dissolution uniformity (RSD <5%).

- Food Conglomerates: Extended probiotic shelf life from 6 to 12 months as a carrier.

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VI. Ulwazi Lokuxhumana

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- Global Website: www.silica-specialist.com

- Technical Inquiries: technical.service.aerosil@evonik.com

- China Hotline: +86 21 6119-1151

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Mayelana ne-Evonik

Evonik iyinkampani ehamba phambili emhlabeni jikelele kwezokwenziwa kwezinto ezikhethekile enolwazi lweminyaka engama-50 emithonjeni yezokwelapha, ikhonza u-18 emakhampasini aphezulu angu-20 emhlabeni wezokwelapha. Uchungechunge lwabo lwe-AEROSIL lunomkhiqizo we-35% emakethe yomhlaba wonke we-silica yepharmaceutical-grade, luhambisa ukuhamba phambili okuqhubekayo kwezobuchwepheshe bokulethwa kwemithi.

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注意：产品性能可能因配方和工艺条件而有所不同。建议在使用前进行兼容性测试。Evonik保留在不事先通知的情况下修改技术参数的权利。

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