ZLSIL®-S60A chromatographic grade silica gel
—— Zikhethelo eziqondile, ukuhlanzwa okusebenzayo nokuzivumelanisa kwenqubo yonke
In the core field of chromatographic separation technology, ZLSIL®-S60A chromatographic-grade silica gel stands out with its excellent pore design, surface chemical flexibility, and stability, making it an ideal choice for small molecule separation and purification. As a key material in pharmaceuticals, fine chemicals, and natural products industries, it not only meets the precise analytical needs at the laboratory level but also supports efficient purification for large-scale production, helping customers achieve qualitative leaps in research and development as well as production.
Core performance: redefine the standard of small molecule separation
1. Pore design for specialized small molecules
• 60A (6nm) exclusive aperture: customized for small molecules with molecular weight <2000 Da. Uniform pore structure avoids molecular exclusion effect, ensuring that polar/non-polar compounds (such as drug intermediates and natural product monomers) can enter the pore efficiently, achieving deep retention and accurate separation.
• High specific surface area (497 m²/g): Provides sufficient adsorption sites and improves the enrichment ability of trace components by 30%, especially suitable for the separation of trace components in complex systems (such as the purification of active ingredients below 0.1% in Chinese medicine extracts).
2. I-chemistry yobuso iyaguquguquka ukuze ihambisane nezindlela eziningi zokufuna
• Iphasi ye-silanol eyinhloko yokuhlukaniswa: ngaphandle kokuguqulwa, ama-alcohol, ama-phenol, ama-alkaloid nezinye izinto ezinamandla ezipholile zingahlukaniswa ngqo nge-hydrogen bond kanye ne-dipole action, futhi i-pH ye-mobile phase ingalungiswa (2-8), ukuze ukujolisa kwephikhi kube nokuguquguquka okuningi.
• One-click switch between reverse phase / ion mode: by bonding C18, amino groups and other groups, it is easy to adapt to reverse phase chromatography (separating hydrophobic drugs) or ion exchange mode (purifying organic acids, nucleotides), a set of materials covering the entire range of polar separation requirements.
3. Zombili ukusebenza okusheshayo nokuzinza kuhle kakhulu
• Narrow particle size distribution (mainly 20-40μm): excellent permeability of the column bed, 20% improvement in column efficiency for analytical HPLC, 15% reduction in back pressure for preparative chromatography, and high throughput and high resolution.
• Low metal impurities (Fe³⁺≤0.02%): solve the tailing problem of alkaline compounds (such as amines and nucleosides) from the source, and achieve pharmacopoeia grade separation accuracy, suitable for the analysis of peptide drug impurities and other demanding scenarios.
Multi-application: covering the whole scene from R&D to production
1. Umkhakha wezokwelapha: kusukela ekuhloleni ukungcola kuya ekuhlanzeni izithako ezisebenzayo zokwelapha
• Trace impurity analysis: HPLC accurate positioning of impurities below 0.1%, low metal contamination to ensure peak symmetry, and help API quality control.
• Chiral drug separation: After bonding chiral ligand, the separation degree of enantiomers such as omeprazole and paclitaxel is>1.5, which meets the requirements of optical purity detection and large-scale decomposition.
• Peptide / nucleoside purification: avoid irreversible adsorption of basic groups, yield increased by 10-15%, suitable for the production of high-end drugs such as insulin intermediates.
2. Iimichiza eziphezulu: umngane ophumelelayo emiphumeleni yokuhlanganisa
• Ukwenziwa kokuphendula: I-TLC ingakwazi ukuthola ngokushesha i-intermediate, i-HPLC ingakwazi ukukala ngokunembile, futhi inciphise isikhathi sokwenza ngcono inqubo; I-Suzuki iphuzu lokugcina lokuhlanganiswa nokwakhiwa kwe-amide ingahlolwa ngokunembile kakhulu.
• Isomer separation: the separation efficiency of para-xylene and phenolic positional isomers was improved by 25%, solving the problem of purification of structurally similar compounds.
3. Imithetho yemvelo: ochwepheshe ekwandiseni izithako ezisebenzayo
• Direct separation of polar components: flavonoids, saponins, alkaloids and so on do not need complex pretreatment. In the positive mode, the components are enriched in a single injection, and the purification yield of artemisinin and catechin is more than 98%.
• Trace component capture: 高比表面积以增强吸附能力,富集植物精油和海洋生物提取物中的活性物质μg水平,并有助于创新药物的开发。
4. Ukukhulisa ukukhiqiza: impahla yokupakisha efanelekayo ye-chromatography
• Flash Chromatography adaptation: 40-63μm particle size model supports low pressure high flux separation, single batch processing capacity from milligram to gram free switching, strong equipment compatibility (Teledyne ISCO, Biotage, etc.).
• Industriële stabiliteit: pH 2-8 wye reeks van toleransie (binding fase toleransie 1-12), kan herwin word deur te was met algemene oplosmiddels soos metanol en diklorometaan, en die koste van verbruikersgoedere word met 30% verminder.
Izikhombisi zobuchwepheshe: ukulawula ikhwalithi okuqinile ukuze kufezwe ukusebenza okuhle kakhulu
projekti | unit | 标准 | measured value | 核心价值 |
phezulu | I'm sorry, but it seems that there is no text provided for translation. Please provide the text you would like me to translate into Zulu. | Mhlophe uthuli | kuvuma na | Ih purity i intuitive na controllable, na there i no risk of impurity pollution |
Iholo lezi zilinganiso zezinhlayiya | % | ≥80 | 86 | Uniform particle distribution and consistent column efficiency |
Specific surface area (BET) | m²/g | 450-600 | 497 | Strong adsorption capacity, suitable for trace component separation |
Kongrong | ml/g | 0.6-0.8 | 0.73 | Ithuba lesikhala lithuthukisiwe futhi ukumelana nokudluliselwa kwemithwalo kuphansi. |
Metal impurities (Fe³⁺/Cl⁻) | % | ≤0.02 | fika ija standard | Ukwahlukaniswa kwezinto eziphilayo akukhona ukuhamba phansi futhi idatha iyathembeka |
kuhlo ku dryi | wt.% | 3-5 | 3.93 | Low hygroscopicity and stable long-term storage performance |
Careful service: from packaging to application protection
• 包装规格:标准20KG/袋,支持定制包装以满足从实验室试点测试到工业生产的不同规模要求。
• Storage advice: Gcina endaweni eyomile futhi evulekile, gwema uku吸湿或接触挥发性物质. I-shelf life ingafika ezinyangeni eziyi-24, futhi ikhwalithi iyahambisana.
• Technical support: Provide coupling process guidance, chromatographic column filling scheme and customized solutions for difficult problems to help customers quickly establish separation methods.
Thari mabangela okukhetha i-ZLSIL®-S60A
✅ Specialized small molecules: 60A aperture + high specific surface area, the separation efficiency of compounds <2000 Da is increased by 40%;
✅ Mode is boundless: positive phase / reverse phase / ion exchange can be switched at will, and a set of materials covers all polar separation scenarios;
✅ Zikwezo zokunciphisa izindleko nokuthuthukisa ukusebenza: kulula ukuvuselela, isikhathi sokugcina side, futhi izindleko zokusebenzisa ngobuningi zinciphisa ngqo ngo-25%.
Kungaba ukuhlaziywa kokungcolile ekuthuthukisweni kwemithi noma ukuhluza okukhulu ekukhiqizeni amakhemikhali, i-ZLSIL®-S60A i-chromatographic silica gel iye yaba umngane othembekile ekwehlukaniseni kwakho ngekhono layo elizinzile nokuguquguqukayo.
Ngokushesha, thola izixazululo ezikhethekile zokuhlukanisa nokuhlanzwa, ukuze ukuhlukaniswa ngakunye kube neqiniso futhi kulawulwe!
contact way: Tel: 053188737397 E-mail: levin@zhonglian-chem.com official website:www.zhonglian-chem.com |