I-SYLOID® FP Silica

Izithako Ezisebenza Ngezindlela Eziningi Embonini Yezokudla Nezomuthi

GRACE Ithala | Ubuchwepheshe | Ukwethembeka

Izinselele Zokwakheka

Ukwakha imikhiqizo ye-nutraceutical namavithamini kubonisa izinselele eziningi ezibangelwa izinto eziningi. Le mikhiqizo ngokuvamile iqukethe izithako ezahlukahlukene ezisebenzayo, eziletha ubunzima bokwakheka ngenxa yokungafani kosayizi wezinhlayiya, ukuhamba, ukucindezelwa, ukuzwela kumswakama, nokusebenzisana phakathi kwezithako. Ngokwesibonelo, ezinye izithako ezisebenzayo zitholakala ngesimo sezinhlamvu, kanti ezinye zikhona njengezimpuphu ezinhle. Lokhu kuholela ekusabalaleni okubanzi kosayizi wezinhlayiya engxenyeni exutshiwe, okuholela ekungabi nabulungiswa kokusabalala kwezithako ezisebenzayo nokuhluka okukhulu ithebhulethi-kuya-thebhulethi ekudosisweni. Ngaphezu kwalokho, izithako ezivela ezitshalweni zibonisa ukuhluka kwe-lot-to-lot ezicini zomzimba, okwenza inqubo yokwakheka ibe nzima nakakhulu. Ngaphezu kwalokho, izinto zokusetshenziswa ezinefutha noma ezinamathelayo kunzima ukuzihlanganisa ezindaweni ezibunjiwe eziqinile, futhi ubunzima buya ngokuya bubi lapho izithako ezimpuphu ezinhle zikhona ekwakhekeni.

Ukumunca Amanzi

Izitshalo ngokwemvelo zimunca amanzi futhi zithambekele ekumunceni umswakama endaweni ezizungezile. Lokhu kumuncwa kukadonsa kuholela ekwakhekeni kwezinhlanganisela ezinamathelayo ezinamathela kwezinye izithako eziyimpuphu nemishini yokukhiqiza. Ubunzima balolu daba buya ngokuya nge-Relative Humidity (RH) yendawo kanye nomkhawulo obalulekile we-RH lapho isithako silahlekelwa khona izici zaso zokugeleza ngokukhululeka.

Ama-silica e-SYLOID® FP ayimpuphu ye-silica enezimbotshana eziningi, eziminyene. Lapho ifakwa ezakhiweni, ingakwazi ukumunca inani elikhulu lemiswakama, iqinisekise ukuthi izithako ezisebenzayo zihlala zomile futhi zigcina ukugeleza ngokukhululeka kuyo yonke inqubo yokucubungula nokugcina.

Ukuqina

Ngaphandle kokuthuthukisa ukuhamba kwe-powder, ama-SYLOID® FP porous silica gels aphinde athuthukise ukuzinza kwezithako ezithintekayo kumswakama njengezimveliso zemvelo namavithamini. Ngokumunca umswakama phakathi nenqubo yokukhiqiza kanye nokugcinwa komkhiqizo wokugcina, la ma-silica avimbela ukubola kwezithako futhi andise impilo yeshalofu yomkhiqizo.

Izikhawu Zosayizi Womthamo

Umthwalo ophezulu wezithako ezisebenzayo, uhlanganiswe nemikhawulo osayizi bedosi, uvame ukushiya isikhala esincane kakhulu sezithako ezisizayo ekwakhiweni. Ukwakhiwa okuvamile kwe-nutraceutical kuqukethe izithako ezisebenzayo ezingama-70-90%, kanti kuphela u-10-30% okubekelwe izithako ezisizayo. Lo mthwalo ophansi wezithako ezisizayo, uhlanganiswe nokuhlukahluka kwezithako ezisebenzayo ekwakhiweni okukodwa, kwenza kube nzima ukufeza imigomo eyinhloko yokwakhiwa njengokugeleza kahle, isikhathi esifanele sokudilizwa, ubulukhuni obwanele bethebhulethi, nokunciphisa ukudilika.

Ama-silica e-SYLOID® FP angama-excipients asebenza kahle kakhulu futhi enezici eziningi angakwazi ukuhlangabezana nezidingo eziningi zokwakheka ngesikhathi esisodwa. Ngaphezu kwalokho, isisindo sawo esikhulu sisho ukuthi anomthelela omncane osayizi wokugcina womthamo. Ama-silica e-SYLOID® FP we-Grace anciphisa noma axazulule izinselele eziyinhloko zokwakheka.

Izici Eziyinhloko Ze-Silica

Ukusatshalaliswa Kwosayizi Wezimbotshana

Ama-silica e-SYLOID® abonisa ukusatshalaliswa kosayizi wezimbotshana okulawulwa kahle, okuwumngcele, anikeza abakhi izinzuzo ezengeziwe ezihlanganisa ukulawula okungcono komswakama nokusebenzisana okufanayo phakathi kwe-silica nezinto ezimuncwe.

Umthamo Wokumunca

Usayizi wezimbotshana unobuhlobo obukhulu ekuziphatheni kwe-silica kokumunca umswakama. I-silica enezimbotshana ezincane ingamunca umswakama ezingeni eliphansi lokufingqa, isebenza njengomuncisi ongcono. Ngokuphambene, i-silica enezimbotshana ezibanzi imunca amanani amakhulu amanzi ezingeni eliphakeme lokufingqa, okwenza ibe yinhle ezindaweni ezinomswakama omkhulu.

Isifundo Sokuphumelela

Incazelo Yesifundo

I-SYLOID® 244FP silica yahlolwa ngokumelene ne-silica eyenziwe ngemvula ne-pyrogenic (fumed) silica ngokulayisha okwenziwe kahle okungu-1% ekwakhiweni kwamavithamini amaningi. Ukuhamba kwe-powder kwakuchazwa nge-angle of repose, futhi ama-powder ahlanganisiwe ancindezelwa abe amaphilisi ukuze kuhloliswe izici zokusebenza zamaphilisi.

Ifomula Eyisisekelo

| Izithako | % Ukwakheka |

|---------------------------|---------------|

| UVitamin A | 2.0 |

| UVitamin B1 | 2.0 |

| UVitamin B2 | 2.0 |

| UVitamin B3 | 4.0 |

| UVitamin B6 | 0.4 |

| UVitamin B12 | 0.001 |

| I-Biotin | 0.01 |

| I-Folic acid | 0.2 |

| UVitamin C | 15.0 |

| UVitamin D3 | 0.003 |

| MCC | 61.8 |

| AcDiSol | 6.0 |

| PVP K30 | 5.0 |

| SYLOID® FP Silica - Glidant | 1.0 |

| Mg Stearate | 0.5 |

| **Sekele** | **100.0** |

Ukuhamba komgubo kubaluleke kakhulu ekwenzeni amaphilisi; ukungahambi kahle komgubo kuthinta ukufana kwesisindo samaphilisi nokusebenza kahle komshini. Ama-glidant angezwa kumafomula ngokukhethekile ukuthuthukisa izakhiwo zokuhamba zamaxube omgubo.

I-Angle of Repose

I-SYLOID® 244FP silica ne-PERKASIL® SM 660 silica zinikeze ukuhamba okungcono kakhulu kwengxube yamaphilisi, njengoba kukhonjiswa ngamanani aphansi kakhulu e-angle of repose (i-angle ephansi ibonisa ukuhamba okungcono). Lokhu kuhamba okuthuthukisiwe kubangela:

- Ukusabalala okufanayo kwezithako ezisebenzayo

- Ukuthuthukiswa kokungaguquguquki kwesisindo samaphilisi

- Isikhathi sokukhiqiza esincishisiwe

Ukuqina Kwamaphilisi

Amatafulethi akhiqizwe nge-SYLOID® 244FP silica abonise ubulukhuni obudlula obutholwe ngama-silica e-pyrogenic (fumed) kanye ne-precipitated. Ubulukhuni obandayo buvimbela ukuphuka kwamafulethi ngesikhathi sokucubungula, ukupakisha, kanye nokuthutha.

Ukwahluka kobunzima bethebhulethi

Ukwahluka kobunzima bethebhulethi kuyinkinga ejwayelekile ekucindezelweni kwethebhulethi futhi kuthinta ngqo ukulethwa okunembayo kwezithako ezisebenzayo nge-dose. Ukusebenzisa i-SYLOID® 244FP silica njenge-glidant kwaholela ekunciphisweni kokwahluka kobunzima bethebhulethi phakathi kwezinto zonke ze-silica ezihlolelwe, kuqinisekisa ukulethwa kwe-dose okungaguquki.

Ukusebenza kumathuluzi okunomsoco we-powder

Ama-silica kaGrace’s SYLOID® kanye ne-PERKASIL® afaneleka kahle ekwakheni izithako zokudla ezisekelwe kum粉. Ezinhlelweni zokusebenza zamapowder, ukugcina ukuziphatha okukhululekile ngesikhathi sokucubungula kubalulekile ukuze kuncishiswe isikhathi sokungasebenzi kokukhiqiza nokuqinisekisa ikhwalithi yomkhiqizo kanye nokuhlangana. Ukukhululeka kucaciswa njengamandla amapowder okugcina ijubane lokuhamba uma sekuhamba.

Ngalesi sikhathi, ama-silica kaGrace’s SYLOID® kanye ne-PERKASIL® asebenza njengama-agent okukhululeka aphezulu, enza lezi zinto ezibalulekile:

- Vimbela ukuhlanganiswa kwezingxenye futhi usebenze njengomgoqo wezinto ngesikhathi sokucindezela

- Faka futhi ube ne-smooth izindawo zezingxenye zamapowder, kunciphisa ukungqubuzana phakathi kwezingxenye

- Adsorb umswakama owengeziwe wezulu ngaphambi kokuthi udliwe ngamapowder

- Adsorb umswakama kanye ne-oyela ethuthela ngaphandle kwe-matrix yamapowder

Ama-silica kaGrace enziwa ngokwezindinganiso eziphakeme kakhulu, awasabela nanoma yini, futhi ahlinzeka ngokusebenza okukhethekile ekuqinisekiseni ukuhamba kwamahhala – ngisho nasezinhlanganisweni eziyimpuphu eziyinselele kakhulu.

Izinzuzo ze-SYLOID® FP Silica Excipients zokuLawulwa Nokumunca Ukufingqa

- Ukuthuthukiswa kokufana komkhiqizo ngesikhathi sokuhlanganisa

- Ukuthuthukiswa kokusebenza komkhiqizo

- Amazinga aphansi okusetshenziswa, okuholela ezindlekweni eziphansi zokuhlanganisa

- Amandla aphezulu okuthwala izithako ezisebenzayo nezokwelapha

- Ukuvikelwa okusebenzayo ngokumelene nokumunca ukufingqa

- Ukuncishiswa kokukhiqizwa kothuli ngesikhathi sokukhiqiza

- Ukuncishiswa kokuhluka kwesisindo samaphilisi

- Ukuphuka kwamaphilisi okuphansi nokuba lukhuni okuthuthukisiwe

- Ukwanda kwezinga lokukhiqiza

- Ivumela ukucubungula okuqondile kokucindezela, ukuqeda isidingo sokugaywa

Izinzuzo ze-SYLOID® 72FP Silica ne-SYLOID® G 156F* Silica zokuSiza Izicelo Zokuhambisa

Ama-silica e-SYLOID® 72FP kanye ne-SYLOID® G 156F* enzelwe ngokukhethekile njengezinto ezonga izindleko zokuhambisa izithako emikhiqizweni yemithi, zinikeza izinzuzo ezilandelayo:

- Kuthuthukisa ukuhamba kwezithako ezijwayelekile nezinzima kakhulu

- Kunciphisa ukukhiqizwa kothuli, kunciphisa amathuba okungcoliswa ngokuphambene

- Ukuvinjelwa okuncane kokugcwala, okwenza kube lula ukuphatha nokugcina

*Kutholakala kuphela e-Americas

Isifinyezo

Ukukhetha isithako esifanele kuyisinqumo esibalulekile esingathuthukisa kakhulu ukusebenza kahle kokukhiqiza, ikhwalithi yomkhiqizo, nesikhathi sokuqinisekisa ukuthuthukiswa kwezithako – kuyilapho kunqotshwa izinselelo ezijwayelekile ezihlobene nokwakheka kwezithako zokudla okunomsoco namavithamini.

Ukuhlanganisa izithako ze-SYLOID® silica ezimikhiqizweni kuxazulula izinselelo eziningi ezibalulekile ekwenziweni kwemikhiqizo ye-nutraceutical namavithamini. Lezi zithako ze-silica zithuthukisa kakhulu izici zokugeleza kwezixube zempushana, okuvumela abakhiqizi ukuthi bafeze ukuhamba okungaguquki okuholela ekufaniseni okungcono komkhiqizo, ukuthuthukiswa kwamandla amaphilisi, kanye nokunciphiswa kokuhluka kwesisindo samaphilisi.

Ukuthobela Imithetho

Imikhiqizo ye-SYLOID® FP silica yenziwa futhi iqinisekiswe ukuthi ihlangabezana nezidingo zokuhlola ezichazwe ezinguqulweni zakamuva ze:

- USP-NF ye-silicon dioxide

- JPE ye-silicon dioxide enamanzi

- EP ye-colloidal hydrated silica kanye ne-dental-type silica

- I-Chinese National Standard GB25576-2010 Ibanga III

Yonke imikhiqizo ye-FP nayo ihambisana namazinga omhlaba wonke wezithako zokudla, okubandakanya:

- I-Food Chemical Codex (FCC)

- I-EU Directive No. 231/2012 ye-E551

- Izindinganiso Nezibonelo ZaseJapane Zokudla Okungeziwe D326

- Izidingo ze-JECFA ze-Amorphous Silicon Dioxide

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Ukuze uthole ulwazi olwengeziwe nge-SYLOID® FP silica, vakashela i-grace.com

Indlunkulu YakwaGrace Corporation

W. R. Grace & Co.

7500 Grace Drive

Columbia, Maryland 21044 USA

Ucingo.: +1 410.531.4000

Izindawo Zesifunda

**I-Latin America**

São Paulo, Brasil

Ucingo: +55.15.3141.4100

**I-Asia Pacific**

Shanghai, China

Ucingo: +86.21.3325.8288

**I-Europe**

Worms, Germany

Ucingo: +49.6241.40300

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*Ulwazi olwethulwe lapha, luvela ekuhloleni kwethu nasezinkambeni zethu. Lwethulwa ukuze nicubungule futhi niqinisekise. Njengoba izimo zokusebenza zihluka kakhulu, futhi zingekho ngaphansi kokulawula kwethu, siyayihoxisa yonke imiqulu ngemiphumela engase itholakale ngokusebenzisa imikhiqizo yethu. I-W. R. Grace & Co.-Conn. kanye nezinkampani ezingaphansi kwayo ngeke ziphatheke kabi nganoma yikuphi ukulimala noma ukulimaza okwenzeka ngenxa yokufakwa noma ukusetshenziswa okungalungile kwemikhiqizo yayo. I-Grace igodla ilungelo lokushintsha amanani kanye/noma izincazelo ngaphandle kwesaziso sangaphambili.*

**GRACE®**, **PERKASIL®**, kanye kanye **SYLOID®** yizimpawu zokuhweba ezibhaliswe e-United States kanye/noma kwamanye amazwe e-W. R. Grace & Co.-Conn. **TALENT TECHNOLOGY TRUST™** wuphawu lokuhweba lwe-W. R. Grace & Co.-Conn. Uhlu lwama-trademark aluqoqwe kusetshenziswa ulwazi olutholakala eshicilelwe ngesikhathi sokushicilelwa kwaleli bhukwana futhi lungase lungabonisi kahle ubunikazi bama-trademark bamanje noma isimo sawo.

© Ilungelo lobunikazi 2023 W. R. Grace & Co.-Conn. Wonke Amalungelo Agodliwe.

GRACE

Ithalente | Ubuchwepheshe | Ukwethembeka

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