Colloidal silica has many important applications in the high-end pharmaceutical field:
1. Izilungiselelo zezimboni
- Thickening and thixotropic effect: In some semi-solid preparations such as topical gels and plasterings, colloidal silica can increase the viscosity of the preparation, will not flow freely, and is easy to store and transport; When subjected to a certain shear force (such as when smeared), the viscosity will temporarily decrease, making it easy to spread evenly on the skin, and after coating, it can quickly restore the state of high viscosity to avoid the free flow of drugs.
- Adsorption na dispersion: Ku ma-drug a angasulubili, colloidal silica ikwazi uku-adsorb ama-drug particles futhi ivimbele ukuba ahlangane. Kwezinye izinqubo zokuphuza, ivumela ama-drug particles ukuba ahlale ehlukaniswe kahle emanzini.
- Thickening and thixotropic effect: In some semi-solid preparations such as topical gels and plasterings, colloidal silica can increase the viscosity of the preparation, will not flow freely, and is easy to store and transport; When subjected to a certain shear force (such as when smeared), the viscosity will temporarily decrease, making it easy to spread evenly on the skin, and after coating, it can quickly restore the state of high viscosity to avoid the free flow of drugs.
- Adsorption na dispersion: Ku ma-drug a angasulubili, colloidal silica ikwazi uku-adsorb ama-drug particles futhi ivimbele ukuba ahlangane. Kwezinye izinqubo zokuphuza, ivumela ama-drug particles ukuba ahlale ehlukaniswe kahle emanzini.
2. Krem
Colloidal silica increases the consistency of the cream, making it easier for the cream to adhere to the skin. At the same time, it can also prevent the settlement and separation of drug ingredients, ensuring the uniform distribution of drugs. During storage, the cream does not separate the oil phase from the water phase due to gravity, ensuring the accuracy and effectiveness of the drug dose every time it is used.
Colloidal silica increases the consistency of the cream, making it easier for the cream to adhere to the skin. At the same time, it can also prevent the settlement and separation of drug ingredients, ensuring the uniform distribution of drugs. During storage, the cream does not separate the oil phase from the water phase due to gravity, ensuring the accuracy and effectiveness of the drug dose every time it is used.
3. Iinhalants
Njengomsebenzi wokunceda ukuhamba, uthuli lwezidakamizwa lunokuhamba okuhle, kodwa luphinde luthuthukise ukusabalala kothuli lwezidakamizwa, ukuze umuthi ube usabalalisiwe kangcono, ube lula ukufakwa emaphashini, futhi uthuthukise umphumela wokwelapha komuthi.
4, imikhiqizo yokupakisha imithi
- Thuthukisa ukusebenza kokuvikela: Inqubo yokukhiqiza izinto zokupakisha ezitholakala emithini (njengamabhodlela epulasitiki, ukupakisha kwe-blister, njll.), ukwengeza i-colloidal silica kungathuthukisa impahla yokuvikela yalesi sithako. Ngokuthatha amabhodlela epulasitiki njengomfanekiso, kungavimba kahle ukudluliswa kwezinto ezincane ezifana ne-oxygen ne-vapor yamanzi, kuvikele kangcono ukuzinza kwemithi, ikakhulukazi kwezinye izidakamizwa ezilula ukuvuvukala noma ezibucayi emanzini, futhi kungandisa impilo yokugcina yemithi.
- Thuthukisa ukusebenza kokuvikela: Inqubo yokukhiqiza izinto zokupakisha ezitholakala emithini (njengamabhodlela epulasitiki, ukupakisha kwe-blister, njll.), ukwengeza i-colloidal silica kungathuthukisa impahla yokuvikela yalesi sithako. Ngokuthatha amabhodlela epulasitiki njengomfanekiso, kungavimba kahle ukudluliswa kwezinto ezincane ezifana ne-oxygen ne-vapor yamanzi, kuvikele kangcono ukuzinza kwemithi, ikakhulukazi kwezinye izidakamizwa ezilula ukuvuvukala noma ezibucayi emanzini, futhi kungandisa impilo yokugcina yemithi.